A method of computing the effectiveness of an insecticide

Tags: Balanites aegyptiaca, Author, Pages, Mansoura, PHYTOCHEMISTRY Volume, Mansoura Univ, DOI, Harding Preparation, JOURNAL OF ETHNOPHARMACOLOGY Volume, Organic Research Areas: Pharmacology & Pharmacy, Journal of Applied Polymer Science, L. Jagan Mohan Rao, MAGNETIC RESONANCE IN CHEMISTRY, Delile Author, pp, El-Sherbiny, Dept Chem, USA Web of Science Categories, Abdel-Mogib, Egypt, toxicological studies, AFRICAN MEDICINAL PLANT, R. Charles, Issue, Author Keywords, Abd Elaziz M., Special Issue, seed oil, Mortada, Mohamed M., Source, Published, JOURNAL OF INVESTIGATIVE DERMATOLOGY, method Author, Curcuma longa El Demerdash, El Demerdash, Asphodelus microcarpus, ANTHRAQUINONES, DRUG METABOLISM AND PHARMACOKINETICS Volume, Hosny Source, Fac Sci
Content: Molluscicidal activity of Balanites aegyptiaca against Monacha cartusiana Dawidar, AEM (Dawidar, Abd Elaziz M.)[ 1 ] ; Mortada, MM (Mortada, Mohamed M.)[ 2 ] ; Raghib, HM (Raghib, Hanaa M.)[ 2 ] ; Abdel-Mogib, M (Abdel-Mogib, Mamdouh)[ 1 ] Abstract Context: Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. Objective: Study the molluscicidal activity and chemical constituents of seed oil and seed glycosides of B. aegyptiaca against Monacha cartusiana and determine the structure-activity relationship. Materials and methods: Two bioassay methods (residual film application and the leaf dipping technique) were used to evaluate the toxicity effect of the seed oil and glycosides, in concentrations of 1.000, 0.500, 0.250 and 0.125%. The seed oil was analysed by GC/MS. Acid hydrolysis and chromatographic separation were used to study the seed saponins. Results: The bioassay of B. aegyptiaca against the land snail, M. cartusiana, indicated the activity of the seed oil and the high activity of the seed saponins. The seed glycosides gave 30.0, 53.3, 73.0 and 73.3% mortality for concentrations of 0.125, 0.250, 0.500 and 1.00%, respectively. The LC50 values were 0.335 and 0.256%, respectively. The seed oil was analysed by GC/MS. Acid hydrolysis of the seed saponins gave a mixture of diosgenin, yamogenin and 3,5-spirostadiene. Discussion and conclusion: To study the structure-activity relationship, a triterpenoidal saponin and a triterpenoidal saponins rich extract (of Zygophyllum coccenum) were proven to be inactive. Thus, the activity is associated with the steroidal, not triterpenoidal saponins. Moreover, a spirostane aglycone without sugar moiety, was found to be inactive and attained the activity by glycosidation. Accession Number: WOS:000308526600018 Author Keywords: steroidal saponin; triterpenoidal saponin; glycyrrhizic acid; hecogenin acetate Source: PHARMACEUTICAL BIOLOGY Volume: 50 Issue: 10 Pages: 13261329 DOI: 10.3109/13880209.2012.674950 Published: OCT 2012 KeyWords Plus: SAPONINS; FRUITS Reprint Address: Abdel-Mogib, M (reprint author), Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt. Addresses: [ 1 ] Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt [ 2 ] Natl Agr Res Ctr, Inst Plant Protect, Mansoura, Egypt E-mail Address: [email protected]; [email protected] Publisher: INFORMA HEALTHCARE, TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND Web of Science Categories: Plant Sciences; Medical Laboratory technology; Pharmacology & Pharmacy Title: A method of computing the effectiveness of an insecticide Author(s): Abbott, WS Source: Journal of Economic Entomology Volume: 18 Pages: 265-267
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Gingerdione from the rhizomes of Curcuma longa El Demerdash, A (El Demerdash, A.)[ 1 ] ; Dawidar, AM (Dawidar, A. M.)[ 1 ] ; Keshk, EM (Keshk, E. M.)[ 1 ] ; Abdel-Mogib, M (Abdel-Mogib, M.)[ 1 ] ) Reprint Address: El Demerdash, A (reprint author), Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt. Addresses: [ 1 ] Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt E-mail Address: [email protected] Publisher: SPRINGER, 233 SPRING ST, New York, NY 10013 USA Web of Science Categories: Chemistry, Medicinal; Chemistry, Organic Research Areas: Pharmacology & Pharmacy; Chemistry IDS Number: 015UJ ISSN: 0009-3130 REFERENCES 1. G. K. Jayaprakasha, L. Jagan Mohan Rao, and K. K. Sakariah, Trends Food Sci. Technol., 16, 533 (2005). 2. H. P. T. Ammon, M. I. Anazoda, H. Safayhi, B. N. Dhawan, and R. C. Srimal, Planta Med., 58, 26 (1992). 3. S. Y. Park and D. S. H. L. Kim, J. Nat. Prod., 65, 1227 (2002). 4. H. L. Jiang, B. N. Timmermann, and D. R. Gang, J. Chromatogr. A, 21, 1111 (2006). 5. R. Charles, S. N. Garg, and S. Kumar, Fitoterapia, 71, 716 (2000). 6. S. Zaeoung, A. Plubrukarn, and N. Keawpradub, Songklanakarin J. Sci. Technol., 27, 779 (2005). 7. R. P. Adams, Identification of essential oil Components by Gas Chromatography/Mass Spectroscopy, Allured Publish Corporation, Carol Stream, Illinois, USA, 1995. References 1-N. Barzaghi, F. Crema, G. Gatti, G. Pifferi, E. Perucca Pharmacokinetic studies on IdB 1016, a silybin­phosphatidylcholine complex, in healthy human subjects European Journal of Drug Metabolism and Pharmacokinetics, 15 (1990), 333­338 2-L. Baumann How to prevent photoaging Journal of Investigative Dermatology, 125 (2005), pp. xii­xiii 2-Beckmann-Knopp et al., 2000 S. Beckmann-Knopp, S. Rietbrock, R. Weyhenmeyer, R.H. Bцcker, K.T. Beckurts, W. Lang et al.
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Enhanced pH-responsive carrier system based on alginate and chemically modified carboxymethyl chitosan for oral delivery of protein drugs: Preparation and in vitro assessment carbohydrate polymers, 80 (2010), pp. 1125­1136 8-El-Sherbiny et al., 2010 I.M. El-Sherbiny, E.M. Abdel-Bary, D.R.K. Harding Preparation and in vitro evaluation of new pH-sensitive hydrogel beads for oral delivery of protein drugs Journal of Applied Polymer Science, 115 (2010), pp. 2828­2837 9- Flora et al., 1998 K. Flora, M. Hahn, H. Rosen, K. Benner Milk thistle (Silybum marianum) for the therapy of liver disease The American Journal of Gastroenterology, 93 (1998), pp. 139­143
Biodegradable pH-responsive alginate-poly (lactic-co-glycolic acid) nano/micro hydrogel matrices for oral delivery of silymarin El-Sherbiny, IM (El-Sherbiny, Ibrahim M.)[ 1,3 ] ; Abdel-Mogib, M (Abdel-Mogib, Mamdouh)[ 2 ] ; Dawidar, AAM (Dawidar, Abdel-Aziz M.)[ 2 ] ; Elsayed, A (Elsayed, Ahmed)[ 2 ] ; Smyth, HDC (Smyth, Hugh D. C.)[ 1 ] Abstract This study involves the development and characterization of a series of sodium alginate-based pH-responsive hydrogel microspheres encapsulating poly(D,L-lacticco-glycolic acid) (PLGA) nanoparticles (NPs). The effect of the drying technique (airor freeze-drying) on the size of the developed particles was determined. Swelling characteristics at different pH values, in vitro biodegradation and moisture contents of both air-dried and freeze-dried hydrogel particles were investigated. The effect of drying method on the morphology of the particles was also studied using SEM and AFM. Then, the developed alginate-PLGA particles were evaluated as potential carriers, through a new approach, to improve the dissolution, bioavailability and oral sustained release of silymarin, as a model of hydrophobic natural therapeutics. The used silymarin was isolated from the seeds of some native milk thistle (Silybum marianum) ecotypes of delta Egypt and was characterized with the aid of several analytical techniques including; H-1 NMR, UV and FTIR. The obtained data showed a considerable effect of the alginate content and the drying method onto the characteristics of the prepared particles. Also, the results demonstrated that the developed alginate-based hydrogel microparticles encapsulating silymarin-loaded PLGA NPs can be used as biodegradable carriers that can confer sustained oral release of silymarin in addition to enhancing its overall dissolution and oral bioavailability. (C) 2010 Elsevier Ltd. All rights reserved. Accession Number: WOS:000286965300045 Author Keywords: Alginate; Nanoparticles; Silymarin; Oral drug delivery; Hydrogels KeyWords Plus: THISTLE SILYBUM-MARIANUM; MILK THISTLE; FLAVONOID ANTIOXIDANT; PROTEIN DRUGS; CELLS; MICROSPHERES; FIBROSIS; KINASE; NANOPARTICLES; INHIBITION Reprint Address: Smyth, HDC (reprint author), Univ Texas Austin, Coll Pharm, Div Pharmaceut, Austin, TX 78712 USA. Source: CARBOHYDRATE POLYMERS Volume: 83 Issue: 3 Pages: 13451354 DOI: 10.1016/j.carbpol.2010.09.055 Published: JAN 30 2011 Addresses: [ 1 ] Univ Texas Austin, Coll Pharm, Div Pharmaceut, Austin, TX 78712 USA [ 2 ] Mansoura Univ, Fac Sci, Dept Chem, Nat Prod Lab, ET-35516 Mansoura, Egypt [ 3 ] Mansoura Univ, Fac Sci, Dept Chem, Polymer Lab, ET-35516 Mansoura, Egypt E-mail Address: [email protected] Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND Web of Science Categories: Chemistry, Applied; Chemistry, Organic; Polymer Science Research Areas: Chemistry; Polymer Science IDS Number: 716JQ
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Source: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Volume: 63 Issue: 3 Pages: 288-294 DOI: 10.1016/j.ejpb.2005.12.005 Published: JUL 2006 34. Title: Inhalable alginate nanopar cles as an tubercular drug carriers against experimental tuberculosis Author(s): Zahoor, A; Sharma, S; Khuller, GK Source: International Journal OF ANTIMICROBIAL AGENTS Volume: 26 Issue: 4 Pages: 298-303 DOI: 10.1016/j.ijan micag.2005.07.012 Published: OCT 2005 35. Title: A flavonoid an oxidant, silymarin, inhibits ac va on of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and an carcinogenic effects in human prostate carcinoma DU145 cells Author(s): Zi, XL; Grasso, AW; Kung, HJ; et al. Source: CANCER RESEARCH Volume: 58 Issue: 9 Pages: 1920-1929 Published: MAY 1 1998 36. Title: An carcinogenic effect of a flavonoid an oxidant, silymarin, in human Breast cancer cells MDA-MB 468: Induc on of G(1) arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins Author(s): Zi, XL; Feyes, DK; Agarwal, R Source: CLINICAL CANCER RESEARCH Volume: 4 Issue: 4 Pages: 1055-1064 Published: APR 1998
A novel podophyllotoXin Lignan from Justicia heterocarpa Al-Juaid, SS (Al-Juaid, SS); Abdel-Mogib, M (Abdel-Mogib, M) Abstract Chromatographic separation of the extract of Justicia heterocarpa T. ANDERS. afforded, in addition to known fatty acids, terpenoids and steroids, a new podophyllotoxin lignan. Structures were elucidated by spectroscopic methods, and the structure of the new lignan was confirmed by single crystal X-ray diffraction studies, which have shown that there is a Hbonding stabilized dimer. Source: CHEMICAL & PHARMACEUTICAL BULLETIN Volume: 52 Issue: 5 Pages: 507509 DOI: 10.1248/cpb.52.507 Published: MAY 2004 Author Keywords: Justicia heterocarpa; Acanthaceae; podophyllotoxin lignan; X-ray analysis Reprint Address: Abdel-Mogib, M (reprint author), King Abdulaziz Univ, Fac Sci, Dept Chem, POB 80203, Jeddah 21589, Saudi Arabia. Addresses: [ 1 ] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia ResearcherID Numbers: [ ? ] [ 1 researcher(s) included this record in their ResearcherID My Publica on List. Click to view. ] Abdel-Mogib, Mamdouh J-2267-2012 [ View profile at ResearcherID.com ] Publisher: PHARMACEUTICAL SOC JAPAN, 2-12-15-201 SHIBUYA, SHIBUYA-KU, TOKYO, 150, JAPAN Web of Science Categories: Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy Research Areas: Pharmacology & Pharmacy; Chemistry References: 1) Gordaliza M., Castro M. A., del Corral J. M. M., San Feliciano A., Curr. Pharm. Design, 6, 1811--1839 (2000). 2) Giri A., Narasu M. L., Cytotechnology, 34, 17--26 (2000). 3) Empt U., Alfermann A. W., Pras N., Petersen M., J. Appl. Bot.-Angew. Bot., 74, 145--150 (2000). 4) Canel C., Moraes R. M., Dayan F. E., Ferreira D., Phytochemistry, 54, 115--120 (2000). 5) Gopalaiah K., Kavitha J., Kanumuri R. V., Rajasekhar D., Subbaraju G. V., Indian J. Chem. B, 40, 596--600 (2001). 6) Navarro E., Alonso S. J., Alonso P. J., Trujillo J., Jorge E., Perez C., Biol. Pharm. Bull., 24, 254--258 (2001). 7) Rajasekhar D., Subbaraju G. V., Pillai K. R., J. Asian Nat. Prod. Res.,
2, 289--300 (2000). 8) Day S. H., Chiu N. Y., Tsao L. T., Wang J. P., Lin C. N., J. Nat. Prod., 63, 1560--1562 (2000). 9) Chen C. C., Hsin W. C., Huang Y. L., J. Nat. Prod., 61, 227--229 (1998). 10) Leal L. K. A. M., Ferreira A. A. G., Bezerra G. A., Matos F. J. A., Viana G. S. B., J. Ethnopharmacol., 70, 151--159 (2000). 11) De Barros R. F. M., Andrade L. D. C., da Silva N. H., Phyton-Int. J. Exp. Bot., 60, 141--145 (1997). 12) Lorenz P., Stermitz F. R., Ismail L. D., Phytochemistry, 52, 63--66 (1999). 13) Bhattacharyya S., Syn. Commun., 25, 3597--3601 (1995). 14) Abdel-Mogib M., Ezmirly S. T., Basaif S. A., J. Saudi Chem. Soc., 4, 103--108 (2000). 15) Adams R. P., "Identification of Essential Oil Components by GC/MS," Allured PUBLISHING CORPORATION, Illinois, 1995, p. 405
Two new naphthalene and anthraquinone derivatives from Asphodelus tenuifolius Abdel-Mogib, M (Abdel-Mogib, M); Basaif, SA (Basaif, SA) Abstract Chromatographic separation of an ethanolic extract of rhizomes of Asphodelus tenuifolius Cav, (Asphodelaceae) yielded in addition to P-sitosterol, stigmasterol and two anthraquinone deriva ves, 1,8-dimethoxynaphthalene as well as two new naphthalene deriva ves. The new compounds were iden fied as 2-acetyl-8-methoxy-3-methyl-1naphthol and 2-acetyl-1,8-dimethoxy-3-methylnaphthalene. The separated compounds were identified on the basis of IR, MS, H-1 and C-13 NMR data. Accession Number: WOS:000174990700015 KeyWords Plus: RAMOSUS TUBERS Reprint Address: Abdel-Mogib, M (reprint author), King Abdulaziz Univ, Fac Sci, Dept Chem, POB 80203, Jeddah 21589, Saudi Arabia. Addresses: [ 1 ] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia ResearcherID Numbers: [ ? ] [ 1 researcher(s) included this record in their ResearcherID My Publica on List. Click to view. ] Abdel-Mogib, Mamdouh J-2267-2012 [ View profile at ResearcherID.com ] Publisher: GOVI-VERLAG GMBH, PHARMAZEUTISCHER VERLAG GINNHEIMER STRASSE 26, D65760 ESCHBORN, GERMANY Web of Science Categories: Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy Research Areas: Pharmacology & Pharmacy; Chemistry References 1-Title: [not available] Author(s): ABDELFATTAH H Source: ACTA PHARM JUGOSL Volume: 41 Pages: 147 Published: 1991
2. Title: Chemistry of Asphodelus fistulosus Author(s): Abd El-Fattah, Hosny Source: Interna onal Journal of Pharmacognosy Volume: 35 Issue: 4 Pages: 274277 Published: Oct., 1997 3. Title: FREE ANTHRAQUINONES OF ASPHODELUS-ALBUS VAR DELPHINENSIS AND ASPHODELUS-CERASIFER (View record in MEDLINE) Author(s): ABDELGAWAD, M; RAYNAUD, J; NETIEN, G Source: PLANTA MEDICA Volume: 30 Issue: 3 Pages: 232-236 Published: 1976 4. Title: A lupane triterpenoid from Maerua oblongifolia Author(s): Abdel-Mogib, M Source: PHYTOCHEMISTRY Volume: 51 Issue: 3 Pages: 445-448 DOI: 10.1016/S0031-9422(98)00771-7 Published: JUN 1999 5. Title: A BIANTHRONE C-GLYCOSIDE FROM ASPHODELUS-RAMOSUS TUBERS Author(s): ADINOLFI, M; CORSARO, MM; LANZETTA, R; et al. Source: PHYTOCHEMISTRY Volume: 28 Issue: 1 Pages: 284-288 DOI: 10.1016/0031-9422(89)85063-0 Published: 1989 6. Title: A NEW CLASS OF ANTHRAQUINONE-ANTHRONE-C-GLYCOSIDES FROM ASPHODELUS-RAMOSUS TUBERS Author(s): ADINOLFI, M; LANZETTA, R; MARCIANO, CE; et al. Source: TETRAHEDRON Volume: 47 Issue: 25 Pages: 4435-4440 DOI: 10.1016/S0040-4020(01)87112-X Published: JUN 17 1991 7. Title: [Preliminary study on the chemical cons tuents and #microbiologic activity of Asphodelus microcarpus (Salzm. et Viv.)]. Foreign Title: Studio preliminare sui costituenti chimici e sulla attivita microbiologica di estratti di Asphodelus microcarpus (Salzm. et Viv.) (View record in MEDLINE) Author(s): Bonsignore, L; Cottiglia, F; Loy, G; et al. Source: Bolle no chimico farmaceu co Volume: 137 Issue: 6 Pages: 186-90 Published: 1998-Jun 8. Title: [not available]
616-619 Published: AUG 1985 15. Title: ANTHRAQUINONES OF ASPHODELUS-MICROCARPUS Author(s): RIZK, AM; ABDELGAW.MM; HAMMOUDA, FM Source: PHYTOCHEMISTRY Volume: 11 Issue: 6 Pages: 2122-& DOI: 10.1016/S0031-9422(00)90193-6 Published: 1972 16. Title: NEW NAPHTHALDEHYDE FROM HEARTWOOD OF DIOSPYROSMELANOXYLON Author(s): SANKARAM, AV; SIDHU, GS Source: PHYTOCHEMISTRY Volume: 10 Issue: 2 Pages: 458-& DOI: 10.1016/S0031-9422(00)94077-9 Published: 1971 17. Title: THE PRESENCE OF SOME GLYCOSIDASES IN ASPHODELUS-MICROCARPUS Author(s): SISINI A; PICCI V; SEGNI P; et al. Source: Bolle no Societa Italiana Biologia Sperimentale Volume: 54 Issue: 19 Pages: 1794-1799 Published: 1978 18. Title: ANTHRAQUINONES IN ASPHODELUS ALBUS MILLER SSP ALBUS Author(s): UTRILLA, MP; CABO, J; JIMENEZ, J; et al. Source: PHARMAZIE Volume: 44 Issue: 5 Pages: 358-359 Published: MAY 1989 19. Title: [not available] Author(s): VONGEMERT JT Source: AUST J CHEM Volume: 21 Pages: 22023 Published: 1968

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